The 2025 KIX LAC Hub Regional Meeting, held in Antigua, Guatemala from June 18–20, brought together over 100 education leaders from Latin America, the Caribbean, and beyond. Organized by the Knowledge and Innovation Exchange (KIX) Latin America and Caribbean (LAC) Hub, the event aimed to address critical challenges in foundational learning and educational equity. Attendees included representatives from Dominica, El Salvador, Grenada, Guatemala, Guyana, Haiti, Honduras, St Vincent and the Grenadines, St Lucia, Belize, and Bolivia. The meeting highlighted the exacerbated educational disparities caused by the COVID-19 pandemic, which left millions of children excluded from learning systems. Key discussions centered on ensuring access to quality foundational learning as a cornerstone for educational justice and holistic development. The event featured keynote speeches, interactive workshops, and thematic panels, including a Ministerial Panel titled ‘Learning and Foundational Competencies: Policies, Innovations, and Challenges.’ Three primary focus areas were identified: prioritizing educational challenges across Global Partnership for Education (GPE) member countries, sharing successful strategies from GPE KIX research projects, and fostering multi-sector partnerships to develop evidence-based solutions. The meeting culminated in the signing of the Antigua Commitment by Ministers of Education, SUMMA, and the Organisation of Eastern Caribbean States (OECS). This milestone reaffirmed the region’s dedication to creating a more equitable, inclusive, and just educational sector. SUMMA, the leading education research and innovation lab for Latin America and the Caribbean, alongside OECS, spearheads the KIX LAC Hub, promoting knowledge exchange and innovative solutions. The outcomes of the meeting will inform early childhood education policies, pedagogical strategies, and inclusive financing mechanisms. Supported by the Ministry of Education of Guatemala, the event was a collaborative effort between the Global Partnership for Education (GPE), Canada’s International Development Research Centre (IDRC), SUMMA, and OECS. Since its inception in April 2020, the KIX LAC Hub has been instrumental in strengthening education systems across the region.