As of week 39, the Ministry of Public Health’s epidemiological surveillance system has documented 123 maternal deaths, marking a 9% decrease compared to the 135 cases recorded in 2024. Health authorities project a continued downward trend in maternal and infant mortality rates by 2025. However, this overall improvement is overshadowed by significant regional disparities. Provinces such as Santiago, La Altagracia, and Distrito Nacional have reported increases in maternal deaths, with 22, 14, and 7 cases respectively. These figures underscore ongoing challenges in the accessibility and quality of obstetric care, particularly in high-demand areas. Maternal mortality serves as a critical indicator of healthcare quality and is influenced by social determinants like poverty, systemic inefficiencies, and inadequate primary care. Most maternal deaths occur within the public health system, raising concerns about the effectiveness of healthcare personnel and support networks. On the infant mortality front, 1,331 deaths have been reported, reflecting a 22% reduction from the previous year’s 1,700 cases. While provinces like El Seibo, Monseñor Noel, and Monte Plata have shown progress, others such as Independencia, Bahoruco, and Sánchez Ramírez continue to face challenges due to limited healthcare infrastructure. Neonatal mortality, a key measure of perinatal care, has decreased by 16%, from 1,378 to 1,145 deaths. Significant improvements were observed in Monseñor Noel (-63%), Duarte (-43%), San Cristóbal (-39%), Puerto Plata (-38%), and La Altagracia (-35%). However, alarming increases were noted in San José de Ocoa (150%), Independencia (100%), Bahoruco (71%), and Hato Mayor (64%), albeit with smaller absolute numbers. The neonatal group remains the most vulnerable, accounting for the highest number of infant deaths. For nearly three decades, monitoring maternal and infant mortality indicators has been a persistent challenge. Maternal deaths are tracked by hospital committees and reported to the Department of Epidemiology. Experts emphasize the need for greater integration of specialized professionals in public healthcare centers to address these critical issues effectively.