A prominent Jamaican urologist, Dr. Colette Antoine, is advocating for a significant shift in prostate cancer screening practices, urging a move away from the traditional digital rectal examination (DRE) towards the prostate-specific antigen (PSA) blood test. Dr. Antoine highlights the DRE’s limited sensitivity in detecting early-stage prostate cancer, emphasizing the PSA test’s superior ability to identify potential issues before symptoms manifest. Prostate cancer remains the leading cause of death among Jamaican men and the most prevalent cancer in the country. The PSA test measures levels of prostate-specific antigen in the blood, with elevated levels often indicating the presence of cancer. In contrast, the DRE involves a physical examination of the prostate through the rectum, which can miss cancers located on the front wall of the gland. Dr. Antoine’s stance aligns with the British Association of Urological Surgeons (BAUS), which recently criticized the DRE as an outdated and ineffective method. Historically, the DRE has been more widely promoted in Jamaica due to its cost-effectiveness compared to the PSA test, which is more expensive. However, Dr. Antoine stresses that combining both tests offers the most comprehensive screening approach. Despite the social stigma surrounding the DRE, particularly in Jamaica where homophobic attitudes are prevalent, urologist Dr. Dean Wong notes that many men privately consent to the exam without hesitation. Dr. Antoine observes that asymptomatic men are increasingly receptive to screening, partly due to her being a woman, while symptomatic men are more likely to agree due to the urgency of their condition. Younger men, in particular, are becoming more proactive, often opting for multiple screenings annually.